New: A treatment designed for rosacea-prone skin

New: A treatment designed for rosacea-prone skin

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Commonly known as: Gluconolactone, D-Glucono-1,5-lactone, D-gluconic acid delta-lactone, Glucono-delta-lactone.
I.N.C.I. list name: Gluconolactone.
Extraction process: Oxidative fermentation of glucose syrup derived from corn or beet sugar/sugar cane using a fungal strain (Aspergillus niger), followed by several purification steps.
Source: Plant (corn).
Botanical name: Zea mays (corn).
Family: Poaceae.
Part of the plant extracted: Seeds.
Provenance, origin: Austria, France.
Chemical characteristics: Poly-hydroxy acid (P.H.A.); Lactone (cyclic ester) derived from gluconic acid; White and odorless crystalline powder; Soluble in water and ethanol; Molecular mass = 178.15 g/mol; Density: 1.720 g/cm3.
Characteristics: Emulsion, colloidal solution, true aqueous solution.
Dosage required in cosmetic products: As a moisturizing agent: 2 - 4% and one of pH 5.5; As a photoprotective agent: 4 - 8% and one of pH 5.5; As an exfoliating agent: 7 - 15% and one of pH 3.8; As a chelating agent: 2%; As a pH regulator or buffering agent: 0.1 - 2%.
Function: Skin maintenance agent.
Properties: Keratolytic, moisturizing, photo-protective, solvent, antioxidant, soothing, chelating, anti-inflammatory, preservative.
Benefits: All types of skin, especially skin with imperfections (blackheads, etc.), acneic skin, mature skin, dull skin and pigmented skin; All types of hair, especially scalps with dandruff.



  • Face care (face serums, masks, cleansing gels, toning lotions, peelings, scrubs, tinted serums, moisturizing creams);

  • Body care (washing gels, peelings, hand and foot creams, scrubs);

  • Hair care (conditioners, exfoliating gels, scalp serums).


Store at room temperature in a cool dry place, away from light, moisture and heat.

Contra-Indications and Precautions

There is no contraindication. The care containing gluconolactone can be applied to all the types of skin, even the most sensitive and reactive skins. Indeed, contrary to the A.H.A. (glycolic acid, lactic acid, etc...) and the B.H.A. (salicylic acid, etc...), the gluconolactone has a more important molecular size; it thus penetrates less deeply in the epidermis and consequently to reduce the irritating side effects which we can meet with the A. Nevertheless, as a precaution, we advise you to perform a skin tolerance test in the hollow of your elbow before using this active ingredient.  Unlike other hydroxy acids, PHA (gluconolactone) is not photo-sensitizing.

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Gluconolactone is an organic acid belonging to the category of polyhydroxy acids (PHA). It is present in nature, especially in honey, fruit juices and wine in small quantities. Initially used in food as an additive, it is also widely used as a functional ingredient in cosmetic products. Gluconolactone consists of a lactone ring which, under the hydrolytic action of the skin's moisture, releases gluconic acid, which is the source of the molecule's activity. It also has numerous hydroxylated groups (-OH).