Hyperserborrhea, that is, the overproduction of sebum by the sebaceous glands, is visually manifested by shiny skin and enlarged pores. Managing this type of skin can be quite challenging as it requires finding a balance in your skincare routine by incorporating astringent and purifying products without neglecting hydration. Found in many cosmetics, is vitamin E suitable for oily skin? Learn more.
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Vitamin E and Oily Skin: Is there a Benefit?
Summary
- Vitamin E and Sebum: A Protective Antioxidant Effect
- External intake of Vitamin E: A benefit for oily skin?
- Sources
Published April 16, 2024,
updated on April 16, 2024,
by
Pauline, Chemical Engineer
—
5 min read
Vitamin E and Sebum: A Protective Antioxidant Effect.
The vitamin E refers to a group of eight fat-soluble molecules, meaning they are soluble in fats: 4 tocopherols and 4 tocotrienols. Classified as essential, it is not synthesised by the body but is provided by the diet, mainly in the form of α-tocopherol. Vitamin E plays a major role in individual health and is particularly involved in reducing cardiovascular risk by acting on cholesterol levels. Considered a marker of acne severity, it is also found in sebum, where it protects its composition. In adults, sebum is made up, on average, of 57.5% triglycerides, 26% wax esters, 12% squalene, 3% cholesterol esters, and 1.5% cholesterol.
Beyond abnormally high levels of androgens (testosterone and 5-alpha dihydroxytestosterone) that stimulate the activity of the sebaceous glands, hyperseborrhea can result from a deficiency of vitamin E in the sebum. Indeed, this antioxidant plays a protective role for squalene, one of the first lipids in the skin affected by oxidative stress and free radicals. These are capable of reacting with squalene and oxidising it into squalene peroxide, a comedogenic compound. Studies in vitro have also shown that it triggers the release of inflammatory mediators. Thanks to its chemical structure, vitamin E can inhibit lipid peroxidation by donating a hydrogen, which stabilises free radicals. It then becomes a free radical itself but is relatively stable due to its aromatic character, provided by its double bonds.
Furthermore, a study conducted with 100 volunteers demonstrated that exposing sebum to UV irradiation equivalent to 4 times the minimal erythemal dose (MED) reduced the quantity of vitamin E by 84.2%, that of coenzyme Q10 (CoQ10), another antioxidant found in sebum, by 70%, and only that of squalene by 13%. The same UV dose applied in the absence of vitamin E and CoQ10 resulted in a 90% decrease in the quantity of squalene. For your information, the MED is the smallest amount of light capable of causing sunburn at the site of exposure 24 hours later.
Vitamin E thus plays a crucial protective role for the sebum, inhibiting the peroxidation of its lipid compounds and preventing their comedogenicity.
External intake of Vitamin E: A benefit for oily skin?
The antioxidant properties of vitamin E make it particularly effective for individuals with oily skin. Indeed, as mentioned earlier, hyperseborrhea can be linked to a deficiency of vitamin E in the sebum. The topical application of cosmetics containing this active ingredient could therefore help combat skin issues associated with oily skin, although further research on this topic would be beneficial. It's worth noting that due to its fat-soluble nature, vitamin E can only be incorporated into oily formulations or emulsions.
While the vitamin E found in topical treatments provides several benefits to the skin, particularly for oily skin, it is through oral intake that it is most effective. Some studies mention its antioxidant action on the skin and its cosmetic virtues after 8 to 12 weeks of daily intake, for doses ranging between 100 and 300 mg. In addition to being included in many dietary supplements, vitamin E is found in numerous vegetable oils (peanut oil, olive oil, rapeseed oil, corn oil...) and in cereals. Oilseeds such as walnuts, hazelnuts or almonds as well as certain fatty fish also prove to be interesting sources of vitamin E.
Please note : Vitamin E is not a sebostatic molecule, meaning it does not reduce sebum production. It simply protects its compounds from oxidation, which could potentially make them inflammatory and comedogenic.
Sources
PACKER L. & al. Sebaceous gland secretion is a major physiological pathway for delivering vitamin E to the skin. The Journal of Investigative Dermatology (1999).
LITTARRU G. & al. Lipophilic antioxidants in human sebum and ageing. Free radical research (2002).
SAKUMA T. & MAIBACH H. Oily Skin: An Overview. Skin Pharmacology and Physiology (2011).
ENDLY D. & MILLER R. Oily Skin: A Review of Treatment Options. Journal of Clinical and Aesthetic Dermatology (2017).
ERKEKOGLU P., SANTOS S. & BLUMENBERG M. Vitamin E in Health and Disease: Interactions, Diseases and Health Aspects. Biochemistry (2021).
Mohammed GUIGA's Thesis. Vitamin E: Metabolism, Physiological Role: Benefits and Risks of Supplementation (2021).
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