The brown spots form as a result of melanin accumulation in the skin. This dark brown pigment is an essential element that plays a protective role against UV rays. The production of melanin is triggered by exposure to sunlight. Indeed, UV rays act on tyrosine, an amino acid, and, thanks to the enzyme tyrosinase, trigger a cascade of reactions leading to the synthesis of melanin. This process is melanogenesis.
Brown spots gradually form throughout life, as exposure to the sun is repeated. Their shape and size can vary. Brown spots are primarily located on the most sensitive and exposed parts of the body, such as the face, neck, shoulders, arms and legs. They frequently appear around the age of forty, but can also emerge earlier.
Although the sun plays a significant role in the development of brown spots, other factors can also contribute to this phenomenon. Indeed, smoking, pollution, or an unbalanced diet can lead to a oxidative stress within the body's cells, that is, the production of free radicals. These reactive oxygen species then cause damage to the DNA and accelerate skin ageing.
Finally, the melasma is a type of brown spot directly linked to a hormonal change. During pregnancy, the level of oestrogen in the body significantly increases, which induces an overproduction of melanin.