If you do not notice an improvement in your skin after six to eight weeks of regular use of cosmetic products targeting pustules, if these multiply rapidly or become a significant source of insecurity, it is time to consult a dermatologist. They can offer you stronger treatments tailored to your situation. Oral antibiotics, for example from the tetracycline family, or topical ones, such as erythromycin, are generally prescribed as a first step. In the case of oral antibiotics, they are sometimes combined with benzoyl peroxide or topical retinoids.
Topical retinoids, whether adapalene or tretinoin, are indeed often used to combat pustules as they possess a noteworthy keratolytic effect which allows them to remove dead cells accumulated on the surface of the epidermis and thus unclog the skin's pores. In cases of severe or persistent acne, an oral treatment based on isotretinoin may be considered. It should be noted that due to its teratogenic nature, isotretinoin is strictly contraindicated for pregnant women. Those of childbearing age must imperatively use reliable contraception.
Another option in the case of recurrent pustules: the continuous intake of spironolactone, a diuretic with anti-androgenic properties. By regulating and reducing the production of androgens, this molecule helps to decrease sebum secretion, which aids in combating whiteheads. However, this therapeutic option is relatively recent and has not yet had much follow-up.
Finally, the "Sebacia" laser is increasingly establishing itself as a long-term solution for eliminating pustules. This process is based on the targeted destruction of sebaceous glands. For this, a solution containing gold and silica microparticles is applied to the skin. These penetrate the sebaceous glands and accumulate within them. The microparticles then absorb the energy delivered by the laser radiation emitting at 810 nm, which destroys the sebaceous glands. This treatment not only eliminates skin lesions but also prevents their recurrence by ensuring that the sebaceous glands still at rest do not become inflamed in the future.