Can mandelic acid be combined with other active ingredients?

If you have acne-prone skin, it is beneficial to choose a treatment containing mandelic acid andsalicylic acid. Its advantage over other agents is its synergistic effect with other chemical exfoliants. While mandelic acid functions to remove dead cells on the surface, salicylic acid aids in deeply unclogging the pores. These two active molecules work together to make your skin smooth, radiant and flawless.

Lipophilic and anti-inflammatory, these unique properties make salicylic acid a strong comedolytic agent. A study even revealed that the combination of mandelic acid - salicylic acid is better than glycolic acid peels in the treatment of non-inflammatory acne lesions.

The other AHAs (glycolic acid, lactic acid, tartaric acid...) are also active ingredients that you can combine with mandelic acid. They can help to combat imperfections, as well as other unsightly marks that can affect the epidermis, such as brown spots or lack of radiance, thanks to their exfoliating property which acts at different levels of the epidermis. However, the total concentration of AHAs in the treatment must be taken into consideration: the higher the concentration of fruit acids, the greater the potential irritant effect of the treatment increases. This combination of AHAs can be found in two of our treatments: the peeling mask with 10% AHA and 10% PHA, as well as the exfoliating night cream with 6% AHA.

It is possible to combine mandelic acid with vitamin C. Brightening, depigmenting... vitamin C will "support" the effects of mandelic acid. This combination of active ingredients thus allows you to smooth your skin texture, restore radiance and even out the complexion by fading the appearance of brown spots. However, ensure that it is pure vitamin C (INCI name: Ascorbic Acid). Indeed, these two active principles must be formulated in an acidic solution to act, which is not the case with its derivatives.

It is also possible to combine mandelic acid with the retinol. It is known for its action against signs of ageing. If you wish to prevent the phenomenon of premature skin ageing and maintain the suppleness of your epidermis, this combination is recommended. Indeed, mandelic acid is also beneficial for mature skin. It reduces the appearance of wrinkles and fine lines.

To plump the skin and restore volume, combining mandelic acid with hydrating agents such ashyaluronic acid could be beneficial. By promoting the removal of dead skin cells, mandelic acid helps to keep the skin hydrated. The addition of a hydrating agent will enhance water retention in the layers of the epidermis and give a plumping effect to the skin, as well as helping to diminish dehydration fine lines. It's also worth noting that mandelic acid would be an ideal active ingredient for people with dry skin, particularly mature skin. A study has shown that it has the ability to stimulate sebum production.

The exfoliating effect of mandelic acid, combined with the depigmenting action of arbutin acid, niacinamide or tranexamic acid would be interesting. In addition to promoting the removal of dead skin and the distribution of melanin in the epidermis, the depigmenting actives would also act on the process of melanogenesis, particularly by inhibiting the activity of tyrosinase. Thus, thanks to this combination, skin would regain uniformity.

• SAHU P. & al. Comparative study of the effectiveness and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris. Journal of Cosmetic Dermatology(2019).