The peony is used in the form of cellular extract in skincare. Native peony cells are harvested from certain parts of the plant. They are stimulated and treated to reconstitute the active ingredients. These are then multiplied following an ecological biotechnological process.In skincare, native peony cells help to regulate the basic processes involved in hyperseborrhea.
They act on a key enzyme in the epidermis to limit the overproduction of sebum. This enzyme is 5-alpha reductase, a protein responsible for the activity of testosterone, a hormone primarily involved in sebum production. As a reminder, in sebocytes, testosterone is transformed by the 5-alpha reductase enzyme into dihydrotestosterone (DHT). Following several subsequent biochemical reactions, sebum is produced. Thus, hyperseborrhea is either due to an excessive secretion of androgen or a high activity of 5-alpha reductase. By limiting the activity of 5-alpha reductase, the native peony cells limit the overproduction of sebum and therefore the appearance of imperfections related to pore obstruction.
Furthermore, to prevent the flaking of the epidermis on the surface, peony cells strengthen the water circuit and water retention in the epidermis. Concurrently, they limit the release of interleukin-6 (IL-6), a mediator of inflammation, and substance P, a neuropeptide, which appear during sebum production.
Finally, the native cells of peony enhance cellular respiration which leads to the elimination of toxins.