Does topical application of L-carnitine present any risks?

To date, L-carnitine is considered a well-tolerated cosmetic ingredient, used in facial treatments for oily or blemish-prone skin. Multiple studies have evaluated this compound at concentrations between 0.5% and 2% without causing adverse skin reactions. L-carnitine is suitable for sensitive skin, with no reports of redness, irritation, or itching after topical application of a product containing this ingredient.

With regard to its use in vulnerable groups such as pregnant or breastfeeding women and young children, available data are limited or lacking. However, the L-carnitine topical form is not considered a hazardous cosmetic ingredient during pregnancy, unlike retinoids or salicylic acid, for example. There are in principle no contraindications for pregnant women to use L-carnitine, although as a precaution it is best to consult their doctor.

This relates to the topical application of L-carnitine, not to its oral administration. Oral intake of L-carnitine during pregnancy should be evaluated on a case-by-case basis with a doctor.