Another practice that has been highlighted and considered as a potential trigger for vitiligo is laser hair removal. To recap, this hair removal technique, considered to be permanent, relies on the emission of a light beam that is absorbed by the melanin present in the hair. This energy is then transferred along the hair to the hair bulb, causing their apoptosis, that is, their cell death. While people with vitiligo can theoretically resort to laser hair removal, most practitioners warn them about the risk of developing a Koebner phenomenon, which, as previously explained, is characterised by the appearance of new white patches following skin trauma.
For individuals who initially do not have vitiligo, there is a risk of hypopigmentation. However, this is most often a temporary whitening of the skin, not actual vitiligo. While, as with tattooing, scientific evidence establishing a direct link between laser hair removal and the onset of vitiligo is scarce, a case of vitiligo following hair removal with an Alexandrite laser (755 nm) has been reported. This involved a 28-year-old woman who, following her laser session, had persistent white spots on her legs. After three months of treatment with tacrolimus, an immunosuppressant, and regular UVB laser sessions (308 nm), the macules were still present.
The persistence of lesions three months after treatment suggests that this is not a simple case of transient hypopigmentation, but a genuine case of vitiligo. Although the patient has never been diagnosed with vitiligo before, it can be assumed that she had a genetic predisposition to this disease, and that the laser session has triggered the onset of the dermatosis. However, this is not certain and it raises the question again as to why so few cases have been reported in the scientific literature.
Once again, more scientific evidence would be required to definitively assert that laser hair removal is likely to cause vitiligo in individuals who initially show no signs of the disease.