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Acetyl Tetrapeptide-11
Commonly known as:
Acetyl Tetrapeptide-11, AcTP2.
I.N.C.I. list name:
Acetyl Tetrapeptide-11.
Extraction process:
Chemical synthesis of peptides followed by N-acetylation.
Source:
Synthetic.
Botanical name:
/
Family:
/
Part of the plant extracted:
/
Provenance, origin:
United States.
Chemical characteristics:
Amino acid sequence: proline-proline-tyrosine-leucine; Molecular mass: 530.6 g/mol; Soluble in water; Insoluble in oil.
Characteristics:
Colloidal solution, emulsion, true hydrophilic solution, suspension, foam.
Dosage required in cosmetic products:
From 2 to 10%.
Function:
Skin maintenance agent.
Properties:
Redensifying, firming, regenerating.
Benefits:
All skin types, and particularly mature skin.
Details
Properties
Firming: Strengthening the weakened cohesion between the dermis and epidermis by stimulating the synthesis of collagen and syndecan, a membrane protein that contributes to cell proliferation, cell migration and cell-matrix interactions;
Redensifying, regenerating: Increasing cellular density through stimulation of epidermal keratinocyte proliferation.
Usage
Facial Care(creams, serums, eye contours);
Haircare (shampoos, serums, styling foams);
Makeup (foundation).
Method of Preservation
Store away from light, moisture and heat.
Contraindications, Usage Precautions
The acetyl tetrapeptide-11 is very well tolerated by the epidermis and does not present any health risks, due to the use of minimal doses which only represent a very small percentage of the final formulation.
Find out more
Acetyl Tetrapeptide-11 is a synthetic signal peptide, produced by acetylation between acetic acid and Tetrapeptide-11. Peptides have the ability to penetrate deep into the skin layers to give various commands to skin cells. In particular, Acetyl Tetrapeptide-11 can increase the synthesis of the proteoglycan, syndecan-1, to strengthen the cohesion of the epidermis, improve the structural integrity of the dermo-epidermal junction (epidermal basal membrane), as well as the cohesion between the epidermis and the dermis, which is impaired by ageing, by stimulating the production of collagen by dermal fibroblasts. It also stimulates the proliferation of keratinocytes, thereby increasing cell density.
